Dr. Pachman

  • Professor of Pediatrics, Northwestern University’s Feinberg School of Medicine
  • Director, Disease Pathogenesis Core, Children’s Memorial Research Center
  • Co-Director, Biomedical Research Component, Northwestern University Multipurpose Arthritis and Musculoskeletal Diseases Center
  • Attending Physician, Rheumatology, Children’s Memorial Hospital


Contact Information

  • Phone: 773.880.4303
  • Fax: 773.880.4179
  • E-mail:

Certification

  • American Board of Pediatrics, 1966, 1992, 1999
  • American Board of Allergy & Clinical Immunology, 1974
  • American Board of Pediatrics – Sub-Board Pediatric Rheumatology, 1992, 1999

Education

  • BA, Wellesley College
  • MD, University of Chicago Medical School

Residency/Fellowship

  • Rotating Internship: Philadelphia General Hospital
  • Pediatric Residency: Columbia-Presbyterian’s Babies Hospital
  • NIH post-doctoral fellowship in Immunology: Rockefeller University undefined
  • Honors: NIH post-doctoral fellow; University of Chicago Medical Alumnae: Distinguished Service Award; The Best Doctors In America, 1996

Honors

  • NIH postdoctoral fellow, 1964–1966
  • University of Chicago Medical Alumnae Distinguished Service Award, 1989
  • Listed in “America Best Doctors,” American Health, 1996, 1998, 2000, 2002
  • Erwin Neter Memorial Lecture Award: American Med Lab Immunologists, 1996
  • University of Chicago Alumnae, Professional Achievement Award, 2001
  • Master of Rheumatology, American College of Rheumatology, 2002
  • Am Bd Pediatrics, Ped Rheumatol: Award of Distinction, 2003

Professional Organizations

  • American Association of Immunologists
  • Society of Pediatric Research
  • American Pediatric Society
  • American College of Rheumatology
  • American Association for the Advancement of Science

Offices and Boards

  • Midwest Society for Pediatric Research: Past President
  • Chicago Rheumatism Society: Past President
  • Pediatric Rheumatology Subsection, American Rheumatism Association: Past President
  • National Arthritis Foundation:
  • Blue Ribbon Research Panel (1996)
  • Committee on Education and Patient Services (1994-1996)
  • Chicago Association of Immunologists: President 1997-1999
  • Clinical Immunology Society: Education Committee—current; Laboratory Council: current
  • Board of Directors, Greater Illinois Chapter Arthritis Foundation, 1998-2004

Interests

Dr. Pachman’s clinical and research interests center on the regulation of the immune response, both in children with vascular involvement and rheumatic disease, as well as those with primary immunodeficiency disease. Her specific focus is the study of factors affecting the onset and course of the most common pediatric inflammatory myopathy, juvenile dermatomyositis.

This focus is implemented by both a national NIH funded study of the epidemiology of JDM (JDM – New Onset Juvenile Dermatomyositis Research Registry) and a NIAMS sponsored laboratory based investigation of genetic and immunological factors that may be associated with a short vs. a long disease course. The course of the disease is altered by therapy; prednisone and other steroids are the primary drugs now used to treat pediatric vascular inflammation.

Another study reviews data provided by children admitted to the Clinical Research Center (no patient charges for study) concerning the way that vascular inflammation alters the absorption and metabolism of prednisone when the drug is given by mouth as compared to intravenous administration.

In addition, other new biological agents are under investigation for their effect on JDM and other pediatric rheumatic disease. Further information concerning JDM can be obtained from the JDM web pages.